Linu Balan

Research Scholar

Development of Polymer based Nanoparticle of Marine Derived Anticancer Drugs for Targeted Delivery and Reduction of Toxicity

Development of polymer nanoparticles loaded with marine anticancer drugs as a strategy for targeted therapy for the inhibition of metastasis in breast cancer patients, which could improve the survival rate in patients diagnosed with metastatic breast cancer. Delivery of anticancer compounds using polymeric nanoparticles functionalized with specific molecular markers involved in tumour growth and proliferation will enable targeted delivery to the desired site of action.

Publications

  • Geethakumari, D., Bhaskaran Sathyabhama, A., Raji Sathyan, K., Mohandas, D., Somasekharan, J. V., Thavarool Puthiyedathu, S., 2022. Folate functionalized chitosan nanoparticles as targeted delivery systems for improved anticancer efficiency of cytarabine in MCF-7 human breast cancer cell lines. Int. J. Biol. Macromol. 199, 150–161. https://doi.org/10.1016/j.ijbiomac.2021.12.070 view
  • Deepa, G., Sivakumar, K.C., Sajeevan, T.P., 2018. Molecular simulation and in vitro evaluation of chitosan nanoparticles as drug delivery systems for the controlled release of anticancer drug cytarabine against solid tumours. 3 Biotech 8, 493. https://doi.org/10.1007/s13205-018-1510-x view

Supervising Guide

Dr. Sajeevan T. P.